Yoseph West on Relay Financial’s Path to Scale, Competing Against the Likes of Wells Fargo, and The Power Law in SMB Markets

Yoseph West, co-founder and CEO of Relay Financial, joins Mark MacLeod to discuss building a business banking platform that takes on Chase, Wells Fargo, and thousands of traditional banks. Relay focuses on Main Street SMBs with 2 to 50 employees, […]

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Psychologist Matt Jones on Why Startups Fail Due to Co-Founder Conflict and How to Fix It

Matt Jones, licensed psychologist and co-founder relationship specialist, joins Mark MacLeod to discuss the most underserved relationship in business: the co-founding team. Matt shares the startling statistic that 65% of high-potential startups fail due to co-founder conflict, yet most founding […]

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Amar Varma on AI’s Power Law, OpenAI Alumni Networks, and Building Mantle Against Incumbent Carta

Amar Varma, CEO and co-founder of Mantle, joins Mark MacLeod again, but this time to discuss the dramatic concentration of venture capital, with 41% of 2025’s funding going to just 10 companies. They explore how OpenAI alumni are creating a […]

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Mark MacLeod Unpacks Lessons From 11 of the World’s Most Successful CEOs

In this episode, Mark MacLeod unpacks his study of 11 world-class CEOs whose companies together are valued at over $6 trillion. He shares the surprising routines, decision-making styles, and cultural practices that help leaders like Brian Chesky, Melanie Perkins, and […]

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TechTO’s Marie Chevrier on Sampler’s Rise and Fall and Creating Safe Spaces for Canadian Entrepreneurs

Marie Chevrier spent 10 years building Sampler to a significant scale before losing product market fit due to post-pandemic market shifts, supply chain crises, and rising costs. Rather than staying quiet about the failure, she openly shared her bankruptcy story […]

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Rainbo’s Tonya Papanikolov on Building a Leading Functional Mushroom Brand Through Mind Body Medicine and Kundalini Yoga Practice

Tonya Papanikolov, founder and CEO of Rainbo, shares her journey building one of the leading functional mushroom companies while maintaining deep spiritual practices. In this conversation, she explains the science behind medicinal mushrooms like Lion’s Mane for brain health and […]

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